AG-490 significantly inhibits the constitutive activation of Stat3 in MOPC
contributes to weight loss in mice
Histological data clearly indicate that KDM4B-IN-B3-treated tumors have significant amount of cell apoptosis
Formula: C215H337N65O70S10
Pilaralisib (XL147) inhibits EGF-induced PIP3 production in PC-3 and MCF7 cells in serum-free medium with IC50s of 220 and 347 nM
Cortisol sulfate 507POP146 AG-490 significantly inhibits the constitutiveCortisol sulfate (Cortisol 21 sulfate) is a metabolite of Cortisol (HY N0583). Cortisol sulfate is a specific ligand for intracellular transcortin. Product information CAS Number: 1253 43 6 Molecular Weight: 442. 52 Formula: C21H30O8S Chemical Name: {2 [(1R,3aS,3bS,9aR,9bS,10S,11aS) 1,10 dihydroxy 9a,11a dimethyl 7 oxo 1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH cyclopenta[a]phenanthren 1 yl] 2 oxoethoxy}sulfonic acid Smiles: